| ncRNA name | Nogo-A siRNA |
| ncRNA Category | siRNA |
| Disease name | optic nerve injury |
| Species | Rattus norvegicus |
| Tissues/Cell_line | optic nerves, retinas |
| Methods | transduction, Western blot |
| Expression pattern | associated |
| Functional description | The integrin signaling pathway is regulated by Amino-Nogo, which inhibits optic nerve regeneration and functional recovery, and that the integrin subunit involved might be integrin αv. Nogo-A siRNA treatment significantly increased integrin αv expression and p-FAK levels. |
| PubMed ID | 25612921 |
| Year | 2015 |
| Title | Amino-Nogo inhibits optic nerve regeneration and functional recovery via the integrin αv signaling pathway in rats. |
| Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.